BIPED2 Application Portal

Currently open positions

Elektroniker/in (80%)

Ab 1. Februar 2022 oder nach Vereinbarung

Das Biozentrum der Universität Basel ist eines der weltweit führenden Institute für Life Sciences. Seine 32 Gruppen und 500 Mitarbeitenden erforschen, wie Moleküle und Zellen Leben erschaffen. Dabei decken sie das ganze Spektrum vom Atom bis zum Organismus ab. Das 1971 gegründete Biozentrum ist Geburtsstätte zahlreicher grundlegender Entdeckungen in Biologie und Medizin und hat mehrere Nobelpreisträger hervorgebracht.

Zur Verstärkung unserer Elektronik-Werkstatt suchen wir per 1. Februar 2022 oder nach Vereinbarung eine/n Elektroniker/in.

Die elektronische Werkstatt kümmert sich um die Wartung und Reparatur der Elektronik- und Laborgeräte. Auf Wunsch der Forschenden werden Geräte auch modifiziert oder je nach Bedürfnis – häufig in Zusammenarbeit mit der mechanischen Werkstatt – Spezialanfertigungen entwickelt. Einhergehend mit dem breiten Spektrum der Forschungsthemen am Biozentrum ist dann auch die Bandbreite der nicht handelsüblichen Geräte und Installationen wie beispielsweise Timer, Schrittmotorsteuerungen, Temperaturregler, Sensorenauswertungen, Verstärker, Heizplatten, Mikroskopkühltischen, Detektoren und vieles mehr.

Ihre Aufgaben

  • Reparaturen und Unterhaltsarbeiten an diversen Laborgeräten
  • Entwicklung und Aufbau elektronischer Geräte nach Vorgaben der Wissenschaftler
  • Unterstützung unserer Wissenschaftler bei Versuchsaufbauten

Ihr Profil

  • Abgeschlossene Berufslehre als Elektroniker EFZ
  • Verantwortungsbewusste, teamfähige und offene Persönlichkeit
  • Hohe Service- und Kundenorientierung, sowie eine selbständige Arbeitsweise
  • Gute Deutsch- und Englischkenntnisse in Wort und Schrift
  • Kenntnisse in der Programmierung (Mikrokontroller, Arduino)
Wir wünschen uns eine Persönlichkeit, die Freude daran hat, als Mitglied eines Teams moderne Forschung möglich zu machen. Sie arbeiten zielgerichtet, vorausschauend und umsichtig? Sie reagieren souverän und flexibel auf die vielfältigen Anforderungen im universitären Forschungsumfeld? Sie haben Freude am Umgang mit Menschen aus aller Welt? Dann sind Sie die Person, die wir suchen.

Wir bieten

Wir bieten Ihnen eine abwechslungsreiche Tätigkeit in einem Zweierteam, sowie zeitgemässe Anstellungsbedingungen und Sozialleistungen im Rahmen der universitären Besoldungsordnung. Diese Stelle ist auf zwei Jahre befristet, mit Option auf Festanstellung nach positiver Evaluation.

Bewerbung

Bitte bewerben Sie sich online mit einem Lebenslauf, einem Motivationsschreiben, Arbeitszeugnissen sowie dem Namen/der Adresse von zwei Referenzen.

Die Bewerbungen werden fortlaufend geprüft, bis die Stelle besetzt ist. Bitte beachten Sie, dass nur Online-Bewerbungen akzeptiert werden.

Weitere Auskunft erteilt Ihnen gerne Herr Simon Saner, Tel. 061 207 04 75, E-Mail: s.saner@unibas.ch.
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Bioinformatician / Data Analyst (100%)

The Biozentrum of the University of Basel is one of the leading life sciences institutes in the world. It consists of 30 groups and 500 employees that research how molecules and cells create life, spanning the scale from atom to organism. Founded in 1971, the Biozentrum has been the birthplace of many fundamental discoveries in biology and medicine, spawning several Nobel Laureates.

A bioinformatics data analyst position is available in the group of Mihaela Zavolan, at the Biozentrum, University of Basel. The group combines high-throughput experimental with computational approaches to study many aspects of RNA processing in the context of processes such as organism aging and cancer development.

The expertise of our group members covers the entire spectrum of biomedical research, from molecular biology to computational tool development, data analysis and software engineering. We recently relocated in a new building in a large and very active life science research park that includes multiple research institutes.

We study how gene expression is regulated in mammalian cells, how it is perturbed in diseases and what key factors are responsible for dysregulation.

We are looking for a talented bioinformatician with extensive experience in transcriptome and proteome data analysis to help us integrate data sets generated in our lab or through collaborative projects.


Your profile

You hold a PhD in bioinformatics, computational biology or related field, and you have strong experience in analyzing sequence data (transcriptomes, proteomes, binding data for RNA-binding proteins or transcription factors).


Your position

You work closely with other members of the group to help analyze and integrate high-throughput data sets, supporting ongoing projects in the group as well as our collaborative projects.


We offer

We are a highly interdisciplinary, international and supportive team of scientists, where you will have the opportunity to broaden your horizons, develop new ideas, and engage other team members in implementing and testing your ideas in experimental systems. At the Biozentrum we have access to state-of-the-art facilities for systems-level interrogation of biological systems and a computational infrastructure to match the demands of big data science. We are also part of the Swiss Institute of Bioinformatics and of the NCCR network “RNA and Disease”. The position is for two years. It is available immediately. The call is open until the position is filled.

Basel is an international city with people from 150 nations. Located on the border where Switzerland, Germany, and France meet, Basel is home for a large number of institutions for biomedical research, with numerous possibilities for training, networking and career development. The city provides a high standard of living and a rich and varied cultural atmosphere.


Application / Contact

The application should include a brief personal statement, explaining how your qualifications and experience relate to the role, together with a full, up-to-date CV and contact information of two references. We will review applications starting November 10, 2021 until the position is filled. In all cases, you will be notified of the outcome of your application. Please note that only online applications will be accepted.

For any informal enquiries, please contact Mihaela Zavolan, e-mail: mihaela.zavolan@unibas.ch

Check out a few of our recent publications

On PolyASite: Herrmann CJ et al, doi 10.1093/nar/gkz918

On Sarkopenia: Börsch A et al, doi 10.1038/s42003-021-01723-z

On Bayesian Inference: Breda J et al, doi 10.1038/s41587-021-00875-x

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Postdoctoral Researcher – Development of a bacterial strain to deliver immunomodulatory sRNAs into gut epithelial cells (100%)

Starting in January 2022 or upon mutual agreement

The Biozentrum of the University of Basel is one of the leading life sciences institutes in the world. It consists of 30 groups and 500 employees that research how molecules and cells create life, spanning the scale from atom to organism. Founded in 1971, the Biozentrum has been the birth place of many fundamental discoveries in biology and medicine, spawning several Nobel Laureates.

A postdoctoral position is available in the group of Prof. Marek Basler (www.biozentrum.unibas.ch/basler).

This position is supported by the FreeNovation grant (funded by the Novartis Research Foundation) for the project: “Home delivery: Bacterial sRNA mediated treatment of intestinal bowel disease”.

In this position, the candidate will focus on the development and testing of a commensal bacterium capable of secreting various sRNAs in extracellular vesicles with the goal to modulate immune response of gut epithelial cells.

Your responsibilities are

  • Detect sRNAs in extracellular vesicles (EV) of various gut commensals and pathogens
  • Generate a library of sRNAs with potential immunosuppressive effects
  • Engineer a commensal strain for targeting specific sRNAs for secretion in EVs
  • Validate the ability of EVs to deliver sRNAs to gut epithelial cells
  • Screen sRNA containing EVs in an in vitro human gut epithelial transwell model
  • Analyze data using appropriate statistical methods
  • Present data in a professional format suitable for publication
  • Act as an experienced resource, and demonstrate clear and professional verbal and written communication skills

Your profile

You obtained a PhD in microbiology or cellular/molecular biology. You have a profound expertise in models of diseases, immune response during host-pathogen interaction, RNA sequencing, and genetic manipulation of bacteria. Previous experience with bacterial secretion, gut epithelial cells, and RNA-based methods for manipulation of host-cell expression are of advantage.

We offer

A highly motivated team as part of a multidisciplinary group at the Biozentrum including microbiologists and cell biologists. Moreover, the Biozentrum offers excellent internal support from various core facilities with expert staff as well as a very strong multidisciplinary collaborative environment. Basel is an international city with people from 150 nations. Located on the border between Switzerland, Germany and France, it is Europe’s most important Life Science hub. Basel provides a high standard of living and a rich and varied cultural atmosphere.

The position is available from January 2022 and the funding period is one year.

Application / Contact

Please apply online, and upload the following three separate PDF documents:
  1. Your CV with contacts for three references
  2. Motivation letter explaining why you are a good candidate for this job offer
  3. List of all your publications. For up to three publications most relevant to this job offer describe shortly (up to 200 words) your role as well as why the publication is relevant (for example: what techniques you learned, what experience you gained, etc.).

Incomplete applications will be disregarded. Reviewing of applications will begin in November 2021 and continue until the position is filled.

For any informal enquiries, please contact: basler-recruitment@unibas.ch.
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PhD Fellowship in Mechanobiology

The Biozentrum of the University of Basel is one of the leading life sciences institutes in the world. It consists of 30 groups and 500 employees that research how molecules and cells create life, spanning the scale from atom to organism. Founded in 1971, the Biozentrum has been the birthplace of many fundamental discoveries in biology and medicine, spawning several Nobel Laureates.

Skilled and motivated individuals are encouraged to apply for a 4-year PhD Fellowship in the research group of Roderick Lim at the Biozentrum, University of Basel, Switzerland.


The Lim Lab is interested in understanding how mechanotransduction and nucleocytoplasmic transport (NCT) work in unison to achieve gene expression and cellular phenotypic changes such as during developmental progression, stem cell differentiation and cell transformation.


Your responsibilities

In this project, we want to study how mechanical force impacts on the nuclear pore complexes (NPCs) that mediate NCT. Methods will comprise, amongst others, CRISPR-based genome editing, state-of-the art confocal imaging (including FRET, FRAP, and super-resolution techniques) and atomic force microscopy (AFM).

Besides basic research, PhD candidates will also have to contribute to undergraduate level teaching.


Your profile

Interested candidates should have a background in molecular cell biology, biophysics or related disciplines. Experience in optical/fluorescence imaging or AFM, is a plus. The successful candidate is expected to be highly interactive and capable of independent research in a team environment. A solid command of oral and written English is essential.


We offer

We are a multi-national, interdisciplinary lab that combines biophysical, molecular and cellular approaches to investigate intriguing biological problems. The successful applicant will benefit from a highly stimulating, collaborative research environment as well as state-of-the-art infrastructure and facilities at the new Biozentrum research tower.

Basel is an international city with people from 150 nations. Located on the border where three countries meet - Switzerland-Germany-France - it is Europe’s most important life sciences hub. Basel provides a high standard of living and a rich and varied cultural atmosphere.


Application / Contact

The application should include a cover letter, CV, diplomas and 3 reference letters. Reviewing of applications will start immediately and continue until the position is filled. Please note that only online applications will be accepted.

For further information, please contact stephanie.gehlen@unibas.ch
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Postdoc position: quantitative biology of non-growing bacteria

The Biozentrum of the University of Basel is one of the leading life sciences institutes in the world. It consists of 30 groups and 500 employees that research how molecules and cells create life, spanning the scale from atom to organism. Founded in 1971, the Biozentrum has been the birthplace of many fundamental discoveries in biology and medicine, spawning several Nobel Laureates.

A three-year postdoctoral position is available at the Biozentrum (Basel, Switzerland) in the context of a SNF project led by Dr. Thomas Julou. The position is embedded in the group of Prof. Erik van Nimwegen and the starting date is flexible, between September 2021 and January 2022. The postdoctoral fellow will be supervised by T. Julou and E. van Nimwegen.


The van Nimwegen Lab at Basel University’s Biozentrum is an international and multidisciplinary team with extensive expertise in the field of transcription regulation, cell-to-cell variability, genome evolution, and probabilistic data analysis techniques. A special feature of our group is that it includes both experimental and theoretical researchers which work together to combine cutting edge statistical and computational tools with quantitative experiments. A list of our group's publications can be found on Google Scholar


Your position

The topic of this project concerns Escherichia coli during stationary phase, as a case study of non-growing bacteria. Although bacteria in the wild likely spend the majority of their time in non-growing states, relatively little is known about cell physiology and gene expression in such states, especially at the single-cell level. Our lab uses novel quantitative approaches, such as the one we recently developed to quantitatively track growth and gene expression with single-cell resolution in bacteria exposed to controlled environmental changes [1, 2]. We are interested in both physiological and evolutionary aspects of stationary phase: What are the different physiological states that can be attained during stationary phase? What is the extent and dynamics of cell heterogeneity during stationary, and how does this heterogeneity affect survival, stress-resistance, and the ability of cells to regrow when exposed to new nutrients? Are there evolutionary trade-off(s) between growth-related traits and starvation-related traits? To answer such questions, the candidate is expected to combine experimental techniques from molecular biology, genetics, video-microscopy, microfluidics and microfabrication, with cutting-edge data analysis and modelling techniques, which may be undertaken in collaboration with theoretical researchers in the lab. The project will be tailored to the interests and skills of the successful candidate, and will take advantage of results already obtained by a PhD student in our group.


Your profile

Applicants should have completed a PhD in a relevant field such as biophysics, quantitative biology, microbiology, or evolution. Previous experience with microscopy and microfluidics will be valued. Experience with quantitative analysis and programming skills are a plus as well.


Application / Contact

The application should include a CV and motivation statement as well as the contact details of at least two references. Reviewing of applications will start immediately and continue until the position is filled. Please note that only online applications will be accepted.

For specific questions, feel free to contact Thomas Julou, e-mail: thomas.julou@unibas.ch
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INCATE Test Application

This is the test application for the INCATE program
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