BIPED2 Application Portal

Currently open positions

PhD student position (100%, funded) in synapse-type specific proteome studies

Starting 1 December 2023 or upon agreement

How does life emerge from molecules and cells? This is the central question that motivates us. With curiosity and passion, we investigate the entire spectrum ranging from the atom to the organism. The Biozentrum of the University of Basel is one of the world’s leading life sciences institutes. With 32 groups and 500 employees, we are a dynamic and international research community that has spawned many fundamental discoveries in biology and medicine as well as several Nobel Laureates. Become part of our community!

We are looking to recruit a highly motivated PhD student for an SNF funded project led by Marc van Oostrum in the laboratory of Peter Scheiffele.

The project

In an interdisciplinary project supported by an Ambizione grant of the Swiss National Science Foundation, we will investigate the molecular diversity of synaptic proteomes from in-vivo brain structures (see van Oostrum et. al. 2023 bioRxiv, Cell - in press 2023). Conceptually the research aims at understanding how synaptic proteins determine synapse-type specific connectivity and function. The project integrates molecular neurobiology with systems neuroscience and combines state-of-the-art mass spectrometry-based proteomics technologies with fluorescence activated sorting and in vivo labelling of defined synaptic populations within neuronal circuits. We are looking for a highly motivated student that is excited to learn and develop new technologies in order to drive biology.

Your profile

MSc or equivalent degree with a strong interest in interdisciplinary neurobiology across scales from molecules to circuits. The project involves mass spectrometry-based proteomics, stereotactic surgery, fluorescence-activated cell sorting, genome editing methods, and computational biology. Experience in any of these domains is benefical, but not required. More important are self-motivation, independence and analytical thinking of the applicant. The position is funded and salary is according to institutional guidelines.

We offer

A project at the frontier of science to solve fundamental questions in neurobiology. You will have the unique opportunity to join a small team with close guidance by the SNF Ambizione project grantee Marc van Oostrum while at the same time being embedded in an internationally leading group of dynamic and collaborative scientists, Phd students, postdocs and technicians. The Biozentrum provides a highly stimulating collaborative research environment with a fantastic infrastructure in a brand-new building, as well as state-of-the-art technology platforms for cutting-edge interdisciplinary research.

Basel is an international city with people from 150 nations. Located on the border where three countries meet – Switzerland, Germany and France – it is Europe’s most important life sciences hub. Basel provides a high standard of living and a rich cultural atmosphere.

Application / Contact

Applications should include:
  1. Your up-to-date CV with contact details of at least two referees
  2. A brief personal statement, explaining how your research skills and interests align with the aims of this project and the research focus of our group (max 2 pages)
  3. All required diplomas, including MSc confirmation and grades
  4. Contact of 2 previous mentors for letters of reference

Review of applications will start immediately and continue until the position is filled.
Only online applications will be considered.

For any informal enquiries, please contact: marc.van-oostrum@brain.mpg.de
Apply now

Swiss Nanoscience Institute (SNI) PhD Fellowship

Starting immediately or upon agreement

Skilled and motivated individuals are encouraged to apply for a joint 4-year PhD Fellowship fully funded by the Swiss Nanoscience Institute (SNI) in the research groups of Roderick Lim and Maria Hondele at the Biozentrum, University of Basel, Switzerland.

The Biozentrum of the University of Basel is one of the world’s leading life sciences institutes. With 32 groups and 500 employees, we are a dynamic and international research community that has spawned many fundamental discoveries in biology and medicine as well as several Nobel Laureates.

The Lim Lab is interested in understanding the mechanism(s) of selective transport control in nuclear pore complexes and seeks to replicate such functionality in biomimetic systems. The Hondele Lab focuses on the formation, regulation and function of membraneless organelles, in particular those associated with RNA processing.

The project

The SNI PhD Fellow will combine biophysical, molecular and cellular approaches to study liquid-liquid phase separation (LLPS) with a focus on understanding the exquisite biochemical selectivity and dynamics of biomolecular condensates and membraneless organelles at the nanoscale. Methods will comprise, amongst others, high-speed atomic force microscopy (HS-AFM), fluorescence correlation spectroscopy (FCS), Förster resonance energy transfer (FRET), fluorescence recovery after photobleaching (FRAP), etc..

The SNI PhD Fellow will also contribute to undergraduate level teaching.

Your profile

Interested candidates should have a background in biochemistry, biophysics, nanoscience or related disciplines. Experience in AFM or high-speed (HS-AFM) is a plus. The successful candidate is expected to be highly interactive and capable of independent research in a team environment. A solid command of oral and written English is essential.

We offer

The successful applicant will conduct cutting-edge research using state-of-the-art infrastructure in the Biozentrum, which offers a highly diverse, interdisciplinary, collaborative and stimulating research environment.

Basel is an international city with people from 150 nations. Located on the border where three countries meet - Switzerland-Germany-France - it is Europe’s most important life sciences hub. Basel provides a high standard of living and a rich and varied cultural atmosphere.

Application / Contact

Application deadline: 31 October 2023
Please note that only applications through the online form will be accepted.

The application should include a brief statement of your scientific interests, your research experience, and your particular interest in this open position. In addition, a CV and the contact information of two references is required.

For any informal enquiries, please contact maria.hondele@unibas.ch and roderick.lim@unibas.ch
Apply now

Molecular Biology and Biochemistry Technician/Research Associate (100%)

Starting upon mutual agreement.

How does life emerge from molecules and cells? This is the central question that motivates us. With curiosity and passion, we investigate the entire spectrum ranging from the atom to the organism. The Biozentrum of the University of Basel is one of the world’s leading life sciences institutes. With 32 groups and 500 employees, we are a dynamic and international research community that has spawned many fundamental discoveries in biology and medicine as well as several Nobel Laureates. Become part of our community!

The Mango group is looking to recruit a highly motivated technician/research associate to join the group.

Your responsibilities

We seek a skilled researcher to use imaging methods and modern molecular approaches to study chromatin biology during development. This person will assist and train members of the lab, contribute to lab organization and have a scientific project of their own.

Your profile

Applicants should have a degree in molecular biology or related topics. Previous experience in quantitative imaging, chromatin analysis, and/or molecular biology are highly desirable. The role requires good organizational and communication abilities, and a talent to multi-task. A love of scientific inquiry is critical. The primary language of the laboratory and the Biozentrum is English.

We offer

This position offers an exciting opportunity for a highly motivated individual to contribute to a vibrant research community. The appointment is for one year, with the possibility of extension and ultimately a permanent position.

Application

Please apply online. Please note that only online-applications will be accepted. The application should include a brief personal statement, explaining how your qualifications and experience relate to the role, together with a full, up-to-date CV, diplomas and two reference letters. Review of applications will start immediately and continue until the position is filled.

Apply now

Administrative Assistant (80%)

Starting immediately or as per agreement

How does life emerge from molecules and cells? This is the central question that motivates us. With curiosity and passion, we investigate the entire spectrum ranging from the atom to the organism. The Biozentrum of the University of Basel is one of the world’s leading life sciences institutes. With 32 groups and 500 employees, we are a dynamic and international research community that has spawned many fundamental discoveries in biology and medicine as well as several Nobel Laureates. Become part of our community!

We are looking for an administrative assistant for several research groups.

Your responsibilities are

  • Support of the research group leaders in administrative and organizational matters
  • Organization of courses, lectures and conferences
  • Managing courses and teaching materials using an online system and direct communication with students
  • Support in personnel and financial administration
  • Planning, organization and documentation of meetings
  • Planning and accounting of business trips
  • Assistance to foreign visiting scientists

Your profile

  • Completed commercial training with several years of practice, preferably in a university environment, or University degree in the natural sciences and experience in administration
  • Excellent knowledge of German and English, both written and spoken
  • Confident handling of office software
We are looking for a personality who enjoys making modern research possible as a member of a scientific team. You work in a goal-oriented, forward-looking and prudent manner, are a team player, reliable, well organized and used to working independently? Do you react confidently and flexibly to the diverse demands of the university research environment? Do you enjoy interacting with people from all over the world? Then you are the person we are looking for.

We offer

We offer you a varied job in a team of administrative assistants and as a member of our research groups, as well as contemporary employment conditions and social benefits within the framework of the university salary scale. This position is limited to two years, with an option for permanent employment after a positive evaluation.

Application / Contact

Please apply online with a CV, letter of motivation, reference letters, and the name/address of two references.

Review of applications will start immediately and continue until the position is filled. Please note that only online applications will be accepted.

For any informal enquiries, please contact Manuela Holzer, HR Biozentrum, 061 207 20 22, hr-biozentrum@unibas.ch.
Apply now

PhD student positions (100%, funded) in skeletal muscle plasticity (group of Prof. Christoph Handschin, Biozentrum/University of Basel)

How does life emerge from molecules and cells? This is the central question that motivates us. With curiosity and passion, we investigate the entire spectrum ranging from the atom to the organism. The Biozentrum of the University of Basel is one of the world’s leading life sciences institutes. With 32 groups and 500 employees, we are a dynamic and international research community that has spawned many fundamental discoveries in biology and medicine as well as several Nobel Laureates. Become part of our community!

The project

In an interdisciplinary project supported by a Sinergia grant of the Swiss National Science Foundation, we will investigate the molecular underpinnings of gene regulation in muscle plasticity in health and disease. Thus, in close collaboration with the group of Prof. Sebastian Hiller, comprehensive analysis of RNA-binding, liquid-liquid phase separated condensate formation of transcriptional regulators, coupled to the elucidation of the corresponding structure-function aspects will be performed using various state-of-the-art technologies, spanning from molecular biology to animal (patho)physiology. We are therefore looking for a motivated and well-trained PhD and Postdoc to join the multidisciplinary team of postdocs and PhD students from the Handschin and Hiller groups performing these studies in close collaboration and constant exchange.

Your profile

PhD student applicants should have a MSc or equivalent degree. A strong background in molecular and cell biology is required, optimally in the field of muscle plasticity and physiology. Additional experience in RNA-binding protein biology, liquid-liquid phase separation, NGS-based techniques and analysis (e.g. CLIP or ChIPseq), or proteomics of protein complexes and PTMs is a plus. Selection will furthermore be based on the educational background, motivation, independence and creativity of the applicant. Good knowledge of English is a requirement. The positions are funded, and salaries according to institutional guidelines.

We offer

Our international team consists of a dynamic and collaborative group of scientists, committed to work at the frontier of science and to solve fundamental questions about muscle plasticity. Successful applicants will be embedded at the interface of the Handschin and Hiller groups. The Biozentrum provides a highly stimulating collaborative research environment with a fantastic infrastructure in a brand-new building. Further, we have access to state-of-the-art technology platforms providing the lab with an optimal environment for carrying out cutting-edge interdisciplinary research.

Basel is an international city with people from 150 nations. Located on the border where three countries meet - Switzerland-Germany- France -, it is Europe’s most important life sciences hub. Basel provides a high standard of living and a rich and varied cultural atmosphere.

Application / Contact

Please apply online, enter the relevant information and upload the required PDF documents, including:
  1. Your up-to-date CV with contact details of at least two referees
  2. A brief personal statement, explaining how your research skills and interests align with the aims of this project and the research focus of our group (max 2 pages)
  3. All required diplomas, including MSc confirmation and grades

Review of applications will start immediately and continue until the 15th November noon.

For any informal enquiries, please contact: christoph.handschin@unibas.ch
Apply now

Postdoctoral position (100%, funded) in skeletal muscle plasticity (group of Prof. Christoph Handschin, Biozentrum/University of Basel)

How does life emerge from molecules and cells? This is the central question that motivates us. With curiosity and passion, we investigate the entire spectrum ranging from the atom to the organism. The Biozentrum of the University of Basel is one of the world’s leading life sciences institutes. With 32 groups and 500 employees, we are a dynamic and international research community that has spawned many fundamental discoveries in biology and medicine as well as several Nobel Laureates. Become part of our community!

The project

In an interdisciplinary project supported by a Sinergia grant of the Swiss National Science Foundation, we will investigate the molecular underpinnings of gene regulation in muscle plasticity in health and disease. Thus, in close collaboration with the group of Prof. Sebastian Hiller, comprehensive analysis of RNA-binding, liquid-liquid phase separated condensate formation of transcriptional regulators, coupled to the elucidation of the corresponding structure-function aspects will be performed using various state-of-the-art technologies, spanning from molecular biology to animal (patho)physiology. We are therefore looking for a motivated and well-trained PhD and Postdoc to join the multidisciplinary team of postdocs and PhD students from the Handschin and Hiller groups performing these studies in close collaboration and constant exchange.

Your profile

Postdoctoral applicants should have a PhD or MD/PhD. A strong background in molecular and cell biology is required, optimally in the field of muscle plasticity and physiology. Additional experience in RNA-binding protein biology, liquid-liquid phase separation, NGS-based techniques and analysis (e.g. CLIP or ChIPseq), or proteomics of protein complexes and PTMs is a plus. Selection will furthermore be based on the educational background, motivation, independence and creativity of the applicant. Good knowledge of English is a requirement. The positions are funded, and salaries according to institutional guidelines.

We offer

Our international team consists of a dynamic and collaborative group of scientists, committed to work at the frontier of science and to solve fundamental questions about muscle plasticity. Successful applicants will be embedded at the interface of the Handschin and Hiller groups. The Biozentrum provides a highly stimulating collaborative research environment with a fantastic infrastructure in a brand-new building. Further, we have access to state-of-the-art technology platforms providing the lab with an optimal environment for carrying out cutting-edge interdisciplinary research.

Basel is an international city with people from 150 nations. Located on the border where three countries meet - Switzerland-Germany- France -, it is Europe’s most important life sciences hub. Basel provides a high standard of living and a rich and varied cultural atmosphere.

Application / Contact

Please apply online, enter the relevant information and upload the required PDF documents, including:
  1. Your up-to-date CV with contact details of at least two referees
  2. A brief personal statement, explaining how your research skills and interests align with the aims of this project and the research focus of our group (max 2 pages)
  3. All required diplomas, including PhD and MSc confirmation and grades
  4. List of all your publications and describe briefly (max 300 words) for up to 3 publications what was your role and why they are relevant for the job offer

Review of applications will start immediately and continue until the 15th November noon.

For any informal enquiries, please contact: christoph.handschin@unibas.ch
Apply now

PhD student - molecular microbiology of bacterial biofilms

The Biozentrum of the University of Basel is one of the world’s leading life sciences institutes. With 32 groups and 500 employees, we are a dynamic and international research community that has spawned many fundamental discoveries in biology and medicine as well as several Nobel Laureates.

The research group of Prof. Knut Drescher at the Biozentrum of the University of Basel seeks to appoint a PhD student in molecular microbiology, with a focus on bacterial biofilms, to start immediately or as per arrangement.

The project

The research group of Knut Drescher focuses on understanding the development and functions of bacterial biofilms, particularly in the context of human infections, using controlled laboratory experiments or clinical samples. Biofilms are antibiotic-tolerant bacterial communities that are the cause of many chronic and acute infections, but biofilms are also a model system for understanding basic aspects of multicellular organization in bacteria. The PhD projects on bacterial biofilms be within the broad set of topics investigated within the research group, and will require a background in molecular microbiology. The exact projects are flexible and will be developed together with Knut Drescher, depending on the strengths and interests of the PhD students.

To get an overview of recent projects, take a look at our publications: https://drescherlab.org/publications.html

Your profile

We are looking for highly motivated and talented PhD students to join our lab. A Master degree in biology, biochemistry, biotechnology, bioengineering, or a similar discipline is required. In addition, expertise in molecular microbiology is required. Knowledge in one or more of the following topics is beneficial: biochemistry, metabolism, RNA biology, bacterial genetics, host-pathogen interactions, infection biology.

We offer

We offer a highly interactive, multidisciplinary, and international research group within the Biozentrum. Our group spans expertise in molecular microbiology, biophysics, as well as bioinformatics and the analysis of big datasets. Moreover, the Biozentrum offers excellent internal support from various core facilities with expert staff, and a structured PhD program. Our group embraces diversity and equal opportunity. We are committed to building a team that represents a variety of backgrounds, perspectives, and skills.

Basel is an international city with people from 150 nations, located on the border where Switzerland, Germany, and France meet. A large number of institutions for biomedical research, with numerous possibilities for training, networking, and career development are located in Basel. Basel provides a high standard of living and a rich and varied cultural atmosphere.

Application / Contact

Application deadline: 20 October 2023
Please note that only applications through the online form will be accepted.

The application should include a brief statement of your scientific interests, your research experience, and your particular interest in this open position. In addition, a CV and the contact information of two references is required.

For any informal enquiries, please contact knut.drescher@unibas.ch.

Apply now

Postdoc Position in Biochemistry (100%)

How does life emerge from molecules and cells? This is the central question that motivates us. With curiosity and passion, we investigate the entire spectrum ranging from the atom to the organism. The Biozentrum of the University of Basel is one of the world’s leading life sciences institutes. With 32 groups and 500 employees, we are a dynamic and international research community that has spawned many fundamental discoveries in biology and medicine as well as several Nobel Laureates. Become part of our community!

Professor Anne Spang is recruiting a postdoctoral fellow in Biochemistry to elucidate the structure and function of the FERARI tethering complex.

The project

Inter- and intracellular communication is one of the basics of eukaryotic life. Exo- and endocytic transport are essential components for this communication. Most of the endoytosed material is returned to the plasma membrane through recycling pathways. We have identified a key regulator of the Rab11 recycling pathway, the tethering complex FERARI (Solinger, Rashid et al. Nat. Cell Biol. 2020). FERARI is an unusual tether as it combines membrane fusion and membrane fission activities to promote kiss-and-run of Rab11-positive recycling vesicles with sorting endosomes. More recently, we also showed that FERARI can also promote kiss-and-run of early endocytic Rab5 positive-vesicles with sorting endosomes (Solinger et al., Nat. Comm, 2022). In order to understand how these processes are regulated and coordinated by FERARI, we aim to biochemically elucidate and recapitulate FERARI function in vitro.

Your profile

Interested candidates should hold a PhD and have a proven record in biochemistry. A background in cell biology and/or cryo EM is advantageous. High intrinsic motivation, ability to work independently as well as in a team, perseverance and creativity are expected.

We offer

We are a highly interdisciplinary, international, divers and supportive team of scientists, committed to work at the frontier of science and to solve fundamental questions about cellular function and organization. We offer an interactive environment in which you can broaden your horizon, develop new ideas and your independence, and grow as a scientist and a professional. The Biozentrum of the University of Basel provides a highly stimulating, international and collaborative research environment with state-or-the-art infrastructure and support facilities in a brand-new building.

Basel is an international city with people from 150 nations. Located on the border where Switzerland, Germany, and France meet, Basel is home for a large number of institutions for biomedical research, with numerous possibilities for training, networking and career development. The city provides a high standard of living and a rich and varied cultural atmosphere.

Application / Contact

Please apply online by October 15, 2023.

The application should include a brief personal statement, explaining how your qualifications and experience relate to the role, together with a full, up-to-date CV. Please arrange for at least two reference letters to be sent to anne.spang@unibas.ch.
Review of applications will start immediately. Please note that only online applications will be considered.

For any informal enquiries, please contact: anne.spang@unibas.ch
Apply now

Assistant/Associate Professor position in Infection and Immunity

The Biozentrum of the University of Basel in Switzerland invites applications for a professorship in Infection and Immunity at the tenure-track assistant or tenured associate level. This position will be supported by the Biozentrum and the National Center of Competence in Research (NCCR) "AntiResist: New Approaches to Combat Antibiotic-Resistant Bacteria". The Biozentrum is one of the leading Life Sciences Institutes in the world, investigating how molecules and cells create life, spanning the scale from atom to organism. The NCCR "AntiResist" is a Swiss-wide interdisciplinary center for infection biology and antibiotic research with the University of Basel as home institution.

We seek a creative individual with strong expertise in fundamental research in biology or medicine to investigate important problems in the fields of infection and immunity.

Your position

This professorship will complement and enhance the research portfolio of the Biozentrum and the NCCR "AntiResist", as well as the broader Basel Life Sciences Community, and will contribute to teaching at the undergraduate and graduate level.

Your profile

We are interested in candidates with expertise in the field of Infection and Immunity, including (but not limited to) areas such as host-pathogen interaction, inflammation & immune response, bacterial growth, virulence or response to anti-microbials. We will consider candidates studying animal or human models at the molecular, cellular, tissue or organ/organoid level.

We offer

We offer a very generous research endowment, including support for students, postdocs, technicians and consumables. The Biozentrum is situated in a brand-new building with state-of-the-art core facilities. 30 research groups and 250 postdoctoral fellows and graduate students from more than 50 countries work in fields ranging from structural, computational, cellular and developmental biology to microbiology and neuroscience. The NCCR "AntiResist" comprises a network of academic institutions and collaborating companies in Basel, Zurich and Lausanne consisting of 29 research groups spanning five major disciplines: clinical medicine, engineering, biology, chemistry, and computational biology. The research environment of the Biozentrum and the NCCR "AntiResist" is a stimulating and vibrant environment offering unique opportunities for a wide range of collaborations across disciplines and with other departments. Basel is the home of a vibrant international life sciences community and provides a high standard of living and a superb cultural and cosmopolitan atmosphere.

Application/Contact

Applications (including CV, a list of publications, a letter of motivation, and a two-page summary of past, present and future research) should be addressed to Prof. Dr. Marcel Mayor, Dean of the Faculty of Science and submitted online as one single PDF. During online submission applicants are asked to request three referees to submit confidential letters of reference.

Requests for further information may be addressed to Prof. Dr. Alex Schier (alex.schier@unibas.ch) regarding the Biozentrum of University of Basel and Prof. Dr. Christoph Dehio (christoph.dehio@unibas.ch) regarding NCCR "AntiResist". If your question is about the online application process, please contact the Office of the Dean (dekanat-philnat@unibas.ch).

The deadline for receipt of applications is October 10, 2023. The University of Basel is an equal opportunity and family friendly employer committed to excellence through diversity. We are keenly interested in diversifying our faculty and encourage applications from female candidates.

Apply now

Test Application

This is a test application. Do not apply here - it is only used for testing.

There could be more description text here as well

Apply now

International PhD Program "Biozentrum PhD Fellowships" Winter Call 2023_24

Excellent students from all over the world are encouraged to apply for the prestigious "Biozentrum PhD Fellowships" program. The aim of the fellowships which are sponsored by the Werner Siemens-Foundation and the University of Basel is to select and promote highly talented graduate students in the area of Life Sciences. The fellowships offer direct access to the PhD program of the Biozentrum, University of Basel, additional financial support, a rotation-based selection of the research group, and support for the attendance of scientific meetings and courses during the PhD.
Apply now

New Approaches to Combat Antibiotic-Resistant Bacteria - 2nd Edition - Pre-registration and abstract submission

Description

Scientific Organizers

Heike Broetz-Oesterhelt, Dirk Bumann, Helle Krogh Johansen, Victor Nizet

Date

June 9-13, 2024

Location

Ascona, Switzerland

Summary of the meeting

Over the past decades, pan-resistant strains of major bacterial pathogens have emerged rendering available antibiotics ineffective and putting at risk many achievements of modern medicine. New ways to identify clinically effective antimicrobials are urgently needed. However, the current antimicrobial development pipeline is inadequate because of high attrition and limited coverage of multi-drug resistant Gram-negative bacteria. This conference aligns with the scope of the National Center of Competence in Research “AntiResist” which aims at revitalizing antibiotic discovery by bringing a patient-centered paradigm shift. Such a shift requires a multidisciplinary approach starting at the bedside. Many factors affect the development of novel antibiotics such as our limited understanding of the physiology and heterogeneity of bacterial pathogens in patients and their interactions with microbiota. Bacteria growing in patients experience environments that are very different from standard laboratory conditions used for antibacterial discovery. This conference will review the current knowledge on clinical activity of antibiotics; the role of microbiota; micro-tissue infection models; bacterial physiology in patients; mechanisms of antibacterial candidates, and non-conventional therapies. It will introduce students to emerging concepts that promise to accelerate antibacterial discovery, improve treatment regimens and uncover novel targets for eradicating pathogens. It will bring together world-leading clinicians, microbiologists, tissue engineers and chemists who share common interests in the field and work towards the development of urgently needed control strategies to win the race against superbugs.

Contact

For more information about the conference program, venue, financial assistance, and important deadlines, visit the conference website. For specific questions regarding the registration or financial assistance, contact info@nccr-antiresist.ch

Apply now