BIPED2 Application Portal

Starting 1 December 2022 or as per agreement

The Biozentrum of the University of Basel is one of the leading life sciences institutes in the world. It consists of 32 groups and 500 employees that research how molecules and cells create life, spanning the scale from atom to organism. Founded in 1971, the Biozentrum has been the birthplace of many fundamental discoveries in biology and medicine, spawning several Nobel Laureates.

The Imaging Core Facility (IMCF) of the Biozentrum of the University of Basel is offering a position to a young scientist to enter the field of modern high-end light microscopy.

Your responsibilities

The candidate will support the IMCF by maintaining different state of the art wide-field, confocal, spinning disk, lightsheet (live-cell and cleared samples), multiplexed (seqFISH), and super-resolution (SIM, STORM/PALM) microscopes; will mainly contribute to user training at microscopes and to a lesser extend to image analysis; and will participate in the teaching program of the IMCF. Further information regarding the facility including the detailed list of equipment can be found at https://www.biozentrum.unibas.ch/imcf/

Your profile

We are looking for an enthusiastic person with a technical or research background that combines solid technical expertise with strong communication skills. Suitable candidates are expected to have a university degree in life sciences or physics (master or PhD) and possess practical experience in at least two or more of the following fields: Optics, light microscopy techniques (widefield and/or confocal), live cell imaging. A good knowledge in image processing will be a plus.

The applicant should be rigorous, reliable, well organized and have the flexibility needed for working in a service-oriented context. Good communication skills in English and the ability to operate as a team player in a multi-disciplinary environment are required.

We offer

The Biozentrum offers cutting-edge research infrastructures, a highly international environment, and excellent working conditions. Salary and benefits are according to University of Basel standards.

The position offers an ideal entry point into working in a microscopy facility environment. It is initially for one year with the possibility of further extension. The preferred starting date is December 2022 but can be negotiated.

Application / Contact

Please apply online with a full, up-to-date CV, list of publications, short summary of microscopy experience so far with a list of microscope systems and software, at least one reference letter as well as a motivation letter.

The University of Basel is an equal opportunity employer and encourages applications from all identities and backgrounds.

Reviewing of applications will start on 19 September 2022 and continue until the position is filled. Please note that only online applications will be accepted.

For further information, please feel free to contact Oliver Biehlmaier, PhD, Head of Imaging Core Facility (oliver.biehlmaier@unibas.ch, +41 61 207 20 73).

Starting as soon as possible or upon agreement

The Biozentrum of the University of Basel is one of the leading life sciences institutes in the world. It consists of 32 groups and 500 employees that research how molecules and cells create life, spanning the scale from atom to organism. Founded in 1971, the Biozentrum has been the birth place of many fundamental discoveries in biology and medicine, spawning several Nobel Laureates.

We are seeking a highly motivated analytical Laboratory Technician to join the Proteomics Core Facility (PCF).

The PCF provides state-of-the-art proteomic techniques to support life science research at the Biozentrum. It is tightly integrated in an internationally leading scientific surrounding. The main focus of the group is the set-up of automated sample preparation workflows for proteomics samples with very low starting material and the development of new targeted and global LC-MS workflows for sensitive and precise quantitative analysis of proteins and their modifications.

Your responsibilities

The primary responsibilities for this position will include the operation and maintenance of liquid handling platforms for automated sample preparation (Tecan Evolution for SP3 and TMT workflows, Agilent Bravo AssayMap for phosphorylation enrichment, Tecan A200 for solid phase extraction) as well as general lab management. Main duties will include the development and implementation of new automated preparation workflows for clinical bacteria isolates as well as for internal tissue, bodily fluid and cell samples. The position also includes the possibility to get hands-on training on our LC-MS/MS systems and data analysis tools to carry out independent proteomics analyses.

Your profile

The ideal candidate should have practical experience in preparation workflows of biological samples and in organizing a laboratory. Prior experience in LC-MS analysis (sample preparation, LC-MS workflows and data analysis) as well as operation of liquid handling platforms is not required. The successful candidate should be highly organized, detail-oriented and computer literate. The candidate should have good written and verbal communication skills, be able to work both independently and within a team and have an apprenticeship as laboratory technician (or other degree such as DUT) or higher education (e.g. Bachelor or Master) in a biology or chemistry related subject with 2+ years of experience. High proficiency in spoken and written English is required.

We offer

The position offers a challenging opportunity to join a growing and rapidly evolving bioanalytical field and to work in a team of highly motivated scientists. The position is part of the NCCR “AntiResist” program, initially for 2 years, with the possibility of further extension after positive evaluation. We offer flexible working times and salary and benefits according to University of Basel standards.

Application / Contact

Please apply online with a brief personal statement, explaining how your qualifications and experience make you a good candidate for this job, together with a full, up-to-date CV and addresses of 2 references.

We start reviewing applications from 16 September 2022 until the position is filled. In all cases, you will be notified of the outcome of your application. Please note that only online-applications will be accepted.

For further information, please contact Dr. Alexander Schmidt, Head of Proteomics Core Facility, +41 61 207 2059, alex.schmidt@unibas.ch.

Per 1. November 2022 oder nach Vereinbarung

Das Biozentrum der Universität Basel ist eines der weltweit führenden Institute für Life Sciences. Seine 32 Gruppen und 500 Mitarbeitenden erforschen, wie Moleküle und Zellen Leben erschaffen. Dabei decken sie das ganze Spektrum vom Atom bis zum Organismus ab. Das 1971 gegründete Biozentrum ist Geburtsstätte zahlreicher grundlegender Entdeckungen in Biologie und Medizin und hat mehrere Nobelpreisträger hervorgebracht.

Zur betrieblichen, technischen und logistischen Unterstützung unserer internationalen Forschungsgruppen in der Molekularen Mikrobiologie und Infektionsbiologie sowie des NCCR Programms «AntiResist» suchen wir per 1. November 2022 oder nach Vereinbarung eine(n) motivierte(n), vielseitige(n), flexible(n) und zuverlässige(n) Betriebsassistenten/-in.

Ihre Aufgaben

• Sie sind der erste Ansprechpartner der Forschungsgruppen für alle organisatorischen und technischen Belange.
• Sie stellen den Unterhalt und die Reparaturen von Betriebseinrichtungen, Laborgeräten und Apparaturen sicher.
• Sie unterstützen die Sicherheitsbeauftragte des Biozentrums bei der Umsetzung der Richtlinien und Vorgaben von Arbeitssicherheit und Gesundheitsschutz.
• Sie sind für die Planung und Beschaffung von Einrichtungen, Apparaturen und Verbrauchsmaterial mittels SAP verantwortlich.
• Sie unterstützen die Forschungsgruppenleiter bei der Erstellung und fortlaufenden Kontrolle der Forschungsbudgets.

Ihr Profil

Für diese vielfältige und anspruchsvolle Stelle suchen wir eine belastbare Persönlichkeit mit einem ausgeprägten Sinn für Dienstleistung und Organisationstalent, die es gewohnt ist sowohl selbständig als auch im Team zu arbeiten. Sie verfügen über eine abgeschlossene wissenschaftlich-technische Berufsausbildung und umfangreiche praktische Erfahrung im Laborbereich. Sie kennen die grundlegenden kaufmännischen Abläufe, sind sicher im Umgang mit Office Software und haben idealerweise Erfahrung mit SAP/MM. Sehr gute mündliche und schriftliche Deutsch- und Englischkenntnisse setzen wir voraus.

Wir bieten

Wir bieten Ihnen eine abwechslungsreiche Tätigkeit sowie zeitgemässe Anstellungsbedingungen und Sozialleistungen im Rahmen der universitären Besoldungsordnung.

Bewerbung

Bitte bewerben Sie sich online mit einem Lebenslauf, einem Motivationsschreiben, Arbeitszeugnissen sowie dem Namen/der Adresse von zwei Referenzen.

Die Bewerbungen werden fortlaufend geprüft, bis die Stelle besetzt ist. Bitte beachten Sie, dass nur Online-Bewerbungen akzeptiert werden.

Weitere Auskunft erteilt Ihnen gerne Herr Marcel Scheiwiller, Tel. 061 207 13 13, E-Mail: marcel.scheiwiller@unibas.ch.

Excellent students from all over the world are encouraged to apply for the prestigious "Biozentrum PhD Fellowships" program. The aim of the fellowships which are sponsored by the Werner Siemens-Foundation and the University of Basel is to select and promote highly talented graduate students in the area of Life Sciences. The fellowships offer direct access to the PhD program of the Biozentrum, University of Basel, additional financial support, a rotation-based selection of the research group, and support for the attendance of scientific meetings and courses during the PhD.

The Biozentrum of the University of Basel is one of the leading Life Sciences Institutes in the world. It accommodates 30 research groups and 500 employees investigating how molecules and cells create life, spanning the scale from atom to organism. Founded in 1971, the Biozentrum has been the birthplace of many fundamental discoveries in biology and medicine, spawning several Nobel Laureates.

The National Center of Competence in Research (NCCR) “AntiResist: New approaches to combat antibiotic-resistant bacteria” (2020-2032) is a Swiss-wide interdisciplinary center for antibiotic research with strong collaborations between biologists, clinicians, engineers, computational scientists and chemists. This network is funded by the Swiss National Science Foundation as part of their major support in strengthening research in areas of strategic importance. Our goals are to develop laboratory models mimicking infection processes in human patients, and to use these models to discover innovative antibiotics and alternative strategies to combat antibiotic-resistant bacteria. At the core of this venture are direct links between basic and clinical research, bioengineering, and the pharmaceutical industry to help solving the current antibiotic crisis.

NCCR AntiResist is recruiting for the position of Research Data Officer, 100%.

The position

The Research Data Officer (RDO) is responsible for building and managing the Research Data Ecosystem of the consortium. The RDO is a member of the extended management team of NCCR AntiResist and a member of the Data Management Committee of NCCR AntiResist. The research data of the project will be distributed on a heterogeneous set of existing, and possibly some new data management systems for different types of data (microscopy, next-generation sequencing, proteomics). In collaboration with data providers involved in the project (e.g., technology facilities across the consortium) and with scientific IT platforms at the University Hospital Basel (USB) and University of Basel (sciCORE)), the RDO and the Medical Data Officer (MDO) will coordinate the Data Management Committee to develop and maintain an environment supporting data federation (e.g., cross-linking identifiers at the various service platforms and/or linking data hosted in local data management systems).

Key responsibilities include, but are not limited to the following:

• Together with the MDO, the RDO develops the Research Data Management Strategy (RDS) according to institutional and funder’s guidelines. The RDO and MDO represent the RDS internally (e.g. towards the AntiResist Management) as well as externally (e.g. annually towards the Swiss National Science Foundation (SNSF)).
• The Research Data Officer and the Medical Data Officer coordinate closely in cooperation with the data stakeholders for the implementation of processes and standards.
• Designs and implements the data management environment of the project (database “crawlers” and “scrapers”, monitoring availability of data in federated systems, etc.), with support from software-developer capacity made available through funding of the project.
• Builds and maintains an overview of the data flows in the project.
• In collaboration with institutional technology facilities and their data repositories, sets-up and maintains an overarching database to host and inter-link research data (data federation).
• Develops ETL/ELT scripts tailored to different subject specific databases that store the data generated in the AntiResist project.
• Collaborates with the MDO to merge clinical and experimental research data (different sources, different formats).
• Ensures integrity of the research data and monitors AntiResist scientists for compliance with documentation and sharing policies according to the FAIR principles.
• Assists researchers with data annotation and transfer.
• Assists and proposes metadata schema for the specific data types produced in the project.
• Promoting internal and external data compatibility and data portability in the AntiResist project.
• Ensures that the data reported in the NCCR AntiResist scientific publications comply with the SNSF open science policies.

In execution of these functions, the RDO deals with the data produced by the non-clinical part of the consortium and works with the MDO to merge this data with clinical data. The aim of the consortium is to manage the data according to the FAIR principles (findable, accessible, interoperable, reusable).

Who You Are

For this challenging and exciting position, we are looking for these qualifications:

• MSc or PhD in Computer Science or Bioinformatics with experience in supporting Life Science research, alternatively an equivalent degree in a life science discipline with a strong background in big data and data management/data stewardship.
• Proficient in managing life-science data over the entire data life cycle: from data capture, annotation with controlled vocabularies/ontologies, QC and curation, to publication in domain-specific repositories (e.g. Pride, EGA, PDB, etc.)
• Min. 3 years of experience working in a support role with more than one research data management system (e.g. LIMS (e.g. Labkey), ELN, data type-specific data management system (Omero, Orthanc, etc.).
• Highly proficient with at least one scripting language (Python preferred), including development of interface code between systems using APIs (XML, JSON).
• In-depth understanding of database technologies (SQL, NoSQL; schema design, APIs).
• Thrives on multidisciplinary team collaborations.
• Excellent organizational skills, capable of working autonomously.
• Excellent communication skills (i.e., able to interact and communicate with stakeholders spanning different disciplines and from different background and career stage).
• Networking and cross-functional project management skills.
• Working language is English (oral and written).

We offer

We offer a highly visible, vibrant, inclusive, and flexible international working environment in a network of world-leading research institutes and pharmaceutical companies in Switzerland. The working place is at University of Basel as home institution of the NCCR. The RDO will report to the scientific leadership of the NCCR project and will be embedded in sciCORE, the scientific computing center of University of Basel (https://scicore.unibas.ch/). Salary will be commensurate with institutional guidelines of the University of Basel and level of experience. The position is available immediately. The initial contract is for 1 year, with the expectation to extend to each continued 4-year phase of the NCCR. The position of Research Data Officer is extendable up to the full program ending in 2032.

Application / Contact

The application should include a brief personal statement, explaining how your qualifications and experience make you a good candidate for this job, together with a full, up-to-date CV and addresses of 2 references.

We start reviewing applications from 1 October 2022 until the position is filled. Please note that only online applications via the platform link will be accepted. For further information, please send an email to recruitment@nccr-antiresist.ch